R+R Longevity Serum — Clinical Results

Clinical Results

R+R Longevity Serum — Renovage® + Retinol

A next-generation serum pairing Renovage®, a cellular-longevity active, with a time-release retinol — the gold standard in anti-ageing — to target fine lines, wrinkles, texture, pores and uneven tone.

The ingredient evidence

Renovage® (teprenone)

At its studied dose

A cellular-longevity active that supports the skin as it ages — improving hydration, firmness and tone while softening the look of lines, spots and enlarged pores.

Clinical result Figure
Appearance of main lines (6 months) −47%
Age spots (6 months) −42%
Pore dilation (6 months) −26%
Skin hydration (3 months) +38%
Skin tone / firmness / elasticity (1 month) +15% / +12% / +11%

Method: Supplier clinical study of 3% Renovage on 24 volunteers (mean age 58), measured over 1–6 months. Supplier study of the ingredient; not conducted on the finished Osmotics product.

Time-release retinol

Peer-reviewed

Retinol is the most-studied anti-ageing ingredient. It converts to retinoic acid in the skin, boosting collagen synthesis and inhibiting the matrix metalloproteinases that break collagen down. In a 24-week randomized controlled trial, 0.4% retinol significantly reduced fine wrinkles in naturally aged skin, with biopsy-confirmed new collagen. This serum uses a time-release delivery to reduce the irritation retinol can cause.

Peer-reviewed finding Result
Improvement in fine-wrinkle appearance over 12–24 weeks (review range) ~30–50%

Method: Peer-reviewed clinical literature on topical retinol (e.g., Kafi et al., 24-week RCT). Evidence for the ingredient; the finished serum’s retinol concentration is proprietary. Introduce gradually and use SPF each morning.

Sources: Sederma (Renovage / teprenone) supplier clinical dossier; peer-reviewed topical-retinol literature. Ingredient-level evidence at studied doses, not the finished product. Individual results may vary.