Pentavitin (Saccharide Isomerate): The Complete Guide

Quick answer: Pentavitin® (Saccharide Isomerate) is a plant-derived moisturiser that binds to the skin like a key in a lock and holds water where it counts. Unlike ordinary humectants it stays put through washing, delivering deep, lasting hydration — studies point to relief for up to 72 hours after a single application — which makes it a favourite for chronically dry, tight skin.

What is Pentavitin®?

Pentavitin® is the trade name for Saccharide Isomerate, a carbohydrate complex derived from plants that closely resembles the natural carbohydrate fraction of the skin’s surface. Because it’s so similar to skin’s own moisturising components, it bonds to the outer layer rather than simply sitting on top — the reason its hydration lasts far longer than a typical humectant’s.

How Pentavitin works

Most humectants attract water but wash and rub off easily. Pentavitin® binds to the skin’s keratin like a key fitting a lock, anchoring itself to sites the body doesn’t easily shed. From there it draws and holds water deep in the surface layers, so hydration keeps working through cleansing and across the day. Manufacturer studies describe measurable moisturisation persisting for up to 72 hours after one application.

What does Pentavitin do for skin?

• Deep, long-lasting hydration — relieves tight, parched, dehydrated skin at the source.
• Substantive and wash-resistant — keeps working through cleansing, unlike ordinary humectants.
• Soothes dryness-related discomfort — helps calm the roughness and itch that come with a dry surface.
• Supports the moisture barrier — a well-hydrated surface looks and feels healthier and more resilient.

How to use Pentavitin

Pentavitin® comes formulated into treatments and moisturisers rather than used alone, and suits daily morning and night use. It’s gentle enough for sensitive and dehydrated skin and pairs well with other hydrators like hyaluronic acid and barrier lipids. In our range it appears in targeted treatments including Lipofill and Nécolleté, where lasting hydration supports firmer, smoother-looking skin.

Is Pentavitin safe?

Saccharide Isomerate is plant-derived, gentle and well tolerated, including on sensitive skin. This guide is general education, not medical advice; individual results vary.

Explore our other hydrators in the Ingredient Glossary, or find your match with the skin quiz.

Frequently asked questions

What is Pentavitin?

It’s the trade name for Saccharide Isomerate, a plant-derived moisturiser that binds to the skin for deep, long-lasting hydration.

How is Pentavitin different from hyaluronic acid?

Both hydrate, but Pentavitin bonds to the skin’s surface and resists washing off, so its effect lasts longer. They complement each other well.

How long does Pentavitin’s hydration last?

Manufacturer studies point to measurable moisturisation for up to 72 hours after a single application, because it anchors to the skin rather than rinsing away.

Is Pentavitin good for sensitive skin?

Yes — it’s plant-derived, gentle and well suited to dry, dehydrated and sensitive skin.

Can I use Pentavitin every day?

Yes, morning and night, usually as part of a moisturiser or targeted treatment.

Does Pentavitin help with dryness and tightness?

Yes — it’s specifically valued for relieving chronic dryness, tightness and rough, dehydrated skin.

How long does Pentavitin take to work?

Hydration and comfort are felt quickly and build with continued daily use. Individual results vary.