Nécolleté Age Reversal — Clinical Results
Clinical Results
Nécolleté Age Reversal for Neck & Chest
A firming treatment for the neck and décolleté built on SYN®-HYCAN, a tripeptide that boosts the skin’s own hyaluronan to firm and redefine the contour.
Before & After
See the difference


Photography of an individual user following twice-daily use for 8 weeks. Individual results vary.
The ingredient evidence
Firming tripeptide (SYN®-HYCAN)
At its studied use levelA synthetic tripeptide that raises the skin’s hyaluronan content and increases decorin and lumican — proteoglycans that support new, better-organised collagen. Designed to firm and redefine skin that has begun to sag.
| Clinical result (56 days) | Figure |
|---|---|
| Skin firmness | +29% |
| Skin elasticity | +20% |
| Sagging along the jawline | -7% |
| Felt visibly tightened (consumer) | 91% |
| Felt more moisturised (consumer) | 90% |
Method: Supplier study of a 2.5% SYN®-HYCAN cosmetic formulation, twice daily for 56 days; instrumental measurement and consumer self-assessment. Supplier study of the ingredient; not conducted on the finished Osmotics product.
Lasting hydration (Pentavitin® saccharide isomerate)
Supplier dataA keratin-binding saccharide that anchors to the stratum corneum rather than sitting on the surface, so it resists washing off — for lasting moisture on the thinner skin of the neck and décolleté.
| Supplier hydration data | Figure |
|---|---|
| Skin hydration after one application | +50% |
| Moisture retention | 72h |
| Still more hydrated at 7 days, despite showering | +34% |
Method: Supplier hydration study of the branded ingredient. Its use level in Nécolleté has not been confirmed to us in writing, so these figures are presented as ingredient evidence, not a dose-matched claim for the finished product.
Also in the formula
Supporting activesSoy protein and Rabdosia botanical extracts for a firmer feel, and Osmotics’ Blue Copper peptide.









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