Lipofill Skin Firmness Restoration — Clinical Results

Lipofill Skin Firmness Restoration

A firming serum built on an anti-gravity active dosed at the exact concentration used in the research.

The active: Coheliss®

Dosed at 4.00% — the top of the studied range

Coheliss® (SILAB) is a biomimetic active derived from rye (Secale cereale seed extract). It transposes to the skin the arabinoxylans responsible for rye’s mechanical strength and cohesion, stimulating the skin’s response to mechano-stress — the gravitational load that, over years, pulls the face downwards.

SILAB generated its efficacy data at 3% and 4%. This formula contains Coheliss® at 4.00% — the level at which the tone and tension results below were measured.

+19%skin tone, at 4% (p < 0.05)
+16%skin tension, at 4% (p < 0.05)
−26%wrinkle surface area, nasolabial fold, 56 days vs placebo
−15%wrinkle surface area, crow’s feet, 56 days vs placebo

Study conditions

Active Coheliss® (SILAB) — INCI: Secale cereale seed extract
Dose 4% (tone / tension); 3% (elasticity)
Regimen Twice-daily application, placebo-controlled
Duration 28 days (elasticity, tone) · 56 days (wrinkle surface area)
Elasticity +12.6% improvement in the skin’s ability to return to its initial state vs placebo, at 3%, 28 days

Also in the formula

Pentavitin® at 3.00% — saccharide isomerate, dosed at the level its hydration data was generated at. It binds to keratin in the stratum corneum rather than sitting on the surface, so it resists washing off; supplier studies report hydration sustained for up to 72 hours.

Osilift® (SILAB) at 2.00% — an oat-derived polyose biopolymer that forms a film on the skin surface for an immediate tensor effect. We are not quoting a figure for Osilift®: the supplier’s recommended use level has not yet been confirmed to us in writing, so we cannot state that it is dose-matched.

Squalane, vitamin E and a stearate emulsion base carry the actives and support the barrier.

What we do not claim

This formula also contains Maxi-Lip™ and Hilurlip™, both dosed above their supplier-studied levels. Their published clinical data measures lip volume, lip furrows and lip moisture — not facial firmness. We do not cite those figures here, because the studies did not test the area this product is sold for. Where an active’s evidence does not match the indication, we leave it out.

How to read these claims. Every figure above is an ingredient-level result from the supplier’s own clinical study of the active, at the dose used in that study — not a trial of the finished Osmotics product. What Osmotics can demonstrate is that the active is present at the concentration the research used. A consumer perception study on the finished product is in progress.

Sources: COHELISS®, SILAB. PENTAVITIN®, DSM-Firmenich. Formula: Osmotics Lipofill, batch formula Lab# MA-0963. Individual results vary.

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