Adifyline (Acetyl Hexapeptide-38): The Complete Guide

Adifyline® is a volumising peptide developed to help restore the look of youthful fullness to the face. This guide explains what it is.

What is Adifyline®?

Adifyline® (INCI: acetyl hexapeptide-38) is a peptide studied to support the skin’s own fat cells (adipocytes) in the deeper layers, encouraging the look of localised volume in areas like the cheeks that flatten with age.

What does it do?

  • Supports facial volume — studied for a measured increase in cheek volume over 14 days.
  • Softens a hollow, flat look — for a plumper, more rested appearance.

Where we use it

Adifyline® is carried at its clinically studied dose in Blue Copper 5 PRIME Sleep Tight Mask, working overnight. See the peptides guide. Individual results vary.

Frequently asked questions

What does acetyl hexapeptide-38 do?

It’s a volumising peptide studied to support the look of fullness in areas such as the cheeks that lose volume with age.

How long does it take?

Supplier data measured change over about two weeks; visible results build with consistent use and vary between individuals.